Toxic Metals in the Crude Propolis and Its Transfer Rate to the Ethanolic Extract

Authors

  • Ricardo de Oliveira Orsi Departamento de Produção Animal - Faculdade de Medicina Veterinária e Zootecnia - Universidade Estadual Paulista - UNESP - Campus de Botucatu - São Paulo
  • Daniel Cavalcante Brambila Barros College of Veterinary Medicine and Animal Sciences São Paulo State University (UNESP) Botucatu, SP, Brazil
  • Roney de Carvalho Machedo Silva College of Veterinary Medicine and Animal Sciences São Paulo State University (UNESP) Botucatu, SP, Brazil
  • João Vitor de Queiroz College of Veterinary Medicine and Animal Sciences São Paulo State University (UNESP) Botucatu, SP, Brazil
  • Wellington Luiz de Paula Araújo College of Veterinary Medicine and Animal Sciences São Paulo State University (UNESP) Botucatu, SP, Brazil
  • Alex Junji Shinohara College of Veterinary Medicine and Animal Sciences São Paulo State University (UNESP) Botucatu, SP, Brazil

DOI:

https://doi.org/10.13102/sociobiology.v65i4.3379

Keywords:

Beekeeping, environmental, food safety, toxicity

Abstract

Concentrations of six toxic metals (Ni, Cr, Hg, Cd, Pb and Sn) in 106 samples of Brazilian crude propolis and the transfer rate of these contaminants to ethanolic extract of propolis were evaluated by atomic absorption spectrophotometry. The results show the presence of all the analyzed metals in the samples of crude propolis of São Paulo and Minas Gerais States. Regarding the transfer of these metals to ethanolic extract of propolis, a significant reduction was observed for all metals analyzed. The crude propolis can be considered as an indicator of toxic metals in the environment and the reduction observed in the ethanolic extract of propolis makes the product safe for consumption.

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Author Biography

Ricardo de Oliveira Orsi, Departamento de Produção Animal - Faculdade de Medicina Veterinária e Zootecnia - Universidade Estadual Paulista - UNESP - Campus de Botucatu - São Paulo

Departamento de Produção Animal

References

Aguiar, M.R.M.P., Novaes A.C. & Guarino A.W.S. (2002). Remoção de metais pesados de efluentes industriais por aluminos silicatos. Química Nova, 25: 1145-1154. doi: 10.1590/S0100 40422002000700015

Alloway, B.J. (1990). The origins of heavy metals in soils. In B.J. Alloway (Ed.), Heavy Metals in Soils (29-39 p). New York: Blackie Academic & Professional.

Arslan, S. & Arikan, A. (2013). Accumulation of Heavy Metals in Bee Products Effect of Distance from Highway. Turkish Journal of Agriculture – Food Science and Technology, 1: 90-93. doi: 10.24925/turjaf.vli2.90-93.38

Banskota, A.H., Tezuka, Y. & Kadota, S. (2001). Recent progress in pharmacological research of propolis. Phytotherapy Research, 15: 561–571. doi: 10.1002/ptr.1029

Bezerra, P.S.S., Takiyama, L.R. & Bezerra, C.W.B. (2009). Complexação de íons de metais por matéria orgânica dissolvida: modelagem e aplicação em sistemas reais. Acta Amazonica, 39: 639-648. doi: 10.1590/S0044-59672009000300019

Bonvehí, J.S. & Bermejo, F.J.O. (2013). Element contente of propolis collected from different areas of South Spain. Environmental Monitoring and Assessment, 185: 6035-6047. doi: 10.1007/s10661-012-3004-3

Cain, D.J., Luoma, S.N. & Wallace, W.G. (2004). Linking metal bioaccumulation of aquatic insects to their distribution patterns in a minning-impacted river. Environmental Toxicology and Chemistry, 23: 1463-1473. doi: 10.1897/03-291

Canale, A., Cosci, F., Canovai, R., Giannotti, P. & Benelli, G. (2017). Foreign matter contaminating ethanolic extract of propolis: a fi lth-test survey comparing products from small beekeeping farms and industrial producers. Food Additives & Contaminants, 31: 2022-2025. doi: 10.1080/19440049.2014. 980854

Falcão, S.I., Vilas-Boas, M., Estevinho, L.M., Barros, C., Domingues, M.R.M & Cardoso, S.M. (2010). Phenolic characterization of Northeast Portuguese propolis: usual and unusual compounds. Analytical and Bioanalytical Chemistry, 396: 887-897. doi: 10.1007/s00216-009-3232-8

Finger, D., Filho, I.K., Torres, Y.R. & Quináia, S.P. (2014). Propolis as an indicador of Environmental Contamination by Metals. Bulletin of Environmental Contamination and Toxicology, 92: 259-264. doi: 10.1007/s00128-014-1199-4

Gibbs, R.J. (1973). Mechanisms of Trace Metal Transport in Rivers. Science, 180: 71-73. doi:10.1126/science.180.4081.71

Glinski, Z. (2000). Immuno-supressive and immuno-toxic action of contaminated honey bee products on consumers. Medycyna Weterynary Journal, 56: 634-8

Gong, S., Luo, L., Gong, W., Gao, Y. & Xie, M. (2012). Multivariate analyses of element concentrations revealed the groupings of propolis from different regions in China. Food Chemistry, 134: 583-588. doi: 10.1016/j.foodchem.2012.02.127

Huang, S., Zhang, C.P., Wang, K., Li, G.Q. & Hu, F.L. (2014). Recent Advances in the Chemical Composition of Propolis. Molecules, 19: 19610-19632. doi: 10.3390/molecules191219610

Kunimasa, K., Ahn, M.R., Kobayashi, T., Eguchi, R., Kumazawa S., Fujimori, Y., Nakano, T., Nakayama, T., Kaji, K. & Ohta, T. (2011). Brazilian propolis suppresses angiogenesis by inducing apoptosis in tube-forming endotelial cells through inactivation of survival signal. Evidence-Based Complementary and Alternative Medicine, 2011: 8. doi: 10.1093/ecam/nep024

Liu, H., Chen, L.P., Ai, Y.W., Yang, X., Yu, Y.H., Zuo, Y.B. & Fu, G.Y. (2009). Heavy metal contamination in soil alongside mountain railway in Sichuan, China.Environmental Monitoring and Assessment, 152: 1-4. doi: 10.1007/s10661-008-0293-7

Marcucci, M.C., Ferreres, F., García-Viquera, C., Bankova, V.S., De Castro, S.L., Dantas, A.P., Valente, P.H. & Paulino, N. (2001). Phenolic compounds from Brazilian propolis with pharmacological activities. Journal of Ethnopharmacology, 74: 105-112. doi: 10.1016/S0378-8741(00)00326-3

Onder, S. & Dursun, S. (2006). Air borne heavy metal pollution of Cedruslibani (A. Rich.) in the city centre of Konya (Turkey). Atmospheric Environment, 40: 1122-1133. doi: 10.1016/j.atmosenv.2005.11.006

Orsi, R.O., Funari, S.R.C, Soares, A.M.V.C., Calvi, S.A., Oliveira, S.L., Sforcin, J.M. & Bankova, V. (2000). Immunomodulatory action of propolis on macrophage activation. Journal of Venomous Animals and Toxins including Tropical Diseases, 6: 205-19. doi: 10.1590/S0104-79302000000200006

Orsi, R.O., Sforcin, J.M., Funari, S.R.C., Junior, A.F. & Bankova, V. (2006). Synergistic effect of propolis and antibiotics on the Salmonella thypi. Brazilian Journal of Microbiology, 37: 234-239. doi: 10.1590/S1517-83822006000200002

Popov, B.B., Hristova, V.K., Presilski, S., Shariati, M.A. & Najman, S. (2017) Assessment of heavy metals in própolis and soil from the Pelagoniaregion, Republic of Macedonia. Macedonian Journal of Chemistry and Chemical Engineering, 36: 23-33. doi: 10.20450/mjcce.2017.1004

Sarruge, J.R. & Haag, H.P. (1974). Análises químicas em plantas: Piracicaba: ESALQ, 56 p

Sawidis, T., Breuste, J., Mitrovic, M.., Pavlovic, P. & Tsigaridas, K. (2011). Trees as bioindicator of heavy metal pollution in three European cities. Environmental Pollution, 159: 3560-3570. doi: 10.1016/j.envpol.2011.08.008

Sforcin, J.M. (2007). Propolis and the immune system: a review. Journal of Ethnopharmacology, 73: 243-249. doi: 10.1016/j.jep.2007.05.012

Sonmez, S., Kirilmaz, L., Yucesoy, M., Yucel B & Yilmaz, B. (2005). The effect of bee propolis on oral pathogens and human gingival fi broblast. Journal Ethnopharmacology, 102:371-6. doi: 10.1016/j.jep.2005.06.035

Steinnes, E., Allen, R.O., Petersen, H.M., Rambæk, J.P. & Varskog, P. (1997). Evidence of large scale heavy-metal contamination of natural surface soils in Norway from longrange atmospheric transport. Science of the Total Environment, 205: 255-266. doi: 10.1016/S0048-9697(97)00209-X

Tosic, S., Stojanovic, G., Mitic, S., Pavlovic, A. &Alagic., S. (2017). Mineral composition of selected Serbian própolis samples. Journal of Apicultural Research, 61(1): 5-15. doi: 10.1515/jas-2017-0001

Vishchur, V.Y., Saranchuk, I.I. & Gutiy, B.V. (2016). Fatty acid content of honeycombs depending on the levelof technogenic loadingon the environment. Biosystems Diversity, 24: 182–187. doi: 10.15421/011622

Zar, J.H. (1996). Biostatistical analysis. New Jersey: Pretince Hall, 718 p

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Published

2018-10-11

How to Cite

Orsi, R. de O., Barros, D. C. B., Silva, R. de C. M., Queiroz, J. V. de, Araújo, W. L. de P., & Shinohara, A. J. (2018). Toxic Metals in the Crude Propolis and Its Transfer Rate to the Ethanolic Extract. Sociobiology, 65(4), 640–644. https://doi.org/10.13102/sociobiology.v65i4.3379

Issue

Vol. 65 No. 4 (2018)

Section

Research Article - Bees

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